Multi-ancestry Fine Mapping of Interferon Lambda and the Outcome of Acute Hepatitis C Virus Infection

Clearance of acute infection with hepatitis C virus (HCV) is associated with the chr19q13.13 region containing the rs368234815 (TT/ΔG) polymorphism. We fine-mapped this region to detect possible causal variants that may contribute to HCV-clearance. First, we performed sequencing of IFNL1-IFNL4 regio...

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Udgivet i:Genes Immun
Main Authors: Vergara, Candelaria, Duggal, Priya, Thio, Chloe L., Valencia, Ana, O’Brien, Thomas R., Latanich, Rachel, Timp, Winston, Johnson, Eric O., Kral, Alex H., Mangia, Alessandra, Goedert, James J., Piazzola, Valeria, Mehta, Shruti H., Kirk, Gregory D., Peters, Marion G., Donfield, Sharyne M., Edlin, Brian R., Busch, Michael P., Alexander, Graeme, Murphy, Edward L., Kim, Arthur Y., Lauer, Georg M., Chung, Raymond T., Cramp, Matthew E., Cox, Andrea L., Khakoo, Salim I., Rosen, Hugo R., Alric, Laurent, Wheelan, Sarah J., Wojcik, Genevieve L., Thomas, David L., Taub, Margaret A.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657970/
https://ncbi.nlm.nih.gov/pubmed/33116245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41435-020-00115-3
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