Fine-mapping of genetic loci driving spontaneous clearance of hepatitis C virus infection

Approximately three quarters of acute hepatitis C (HCV) infections evolve to a chronic state, while one quarter are spontaneously cleared. Genetic predispositions strongly contribute to the development of chronicity. We have conducted a genome-wide association study to identify genomic variants unde...

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Pubblicato in:Sci Rep
Autori principali: Huang, Hailiang, Duggal, Priya, Thio, Chloe L., Latanich, Rachel, Goedert, James J., Mangia, Alessandra, Cox, Andrea L., Kirk, Gregory D., Mehta, Shruti, Aneja, Jasneet, Alric, Laurent, Donfield, Sharyne M., Cramp, Matthew E., Khakoo, Salim I., Tobler, Leslie H., Busch, Michael, Alexander, Graeme J., Rosen, Hugo R., Edlin, Brian R., Segal, Florencia P., Lauer, Georg M., Thomas, David L., Daly, Mark J., Chung, Raymond T., Kim, Arthur Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696522/
https://ncbi.nlm.nih.gov/pubmed/29158528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16011-2
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