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Fine-mapping of genetic loci driving spontaneous clearance of hepatitis C virus infection

Approximately three quarters of acute hepatitis C (HCV) infections evolve to a chronic state, while one quarter are spontaneously cleared. Genetic predispositions strongly contribute to the development of chronicity. We have conducted a genome-wide association study to identify genomic variants unde...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Huang, Hailiang, Duggal, Priya, Thio, Chloe L., Latanich, Rachel, Goedert, James J., Mangia, Alessandra, Cox, Andrea L., Kirk, Gregory D., Mehta, Shruti, Aneja, Jasneet, Alric, Laurent, Donfield, Sharyne M., Cramp, Matthew E., Khakoo, Salim I., Tobler, Leslie H., Busch, Michael, Alexander, Graeme J., Rosen, Hugo R., Edlin, Brian R., Segal, Florencia P., Lauer, Georg M., Thomas, David L., Daly, Mark J., Chung, Raymond T., Kim, Arthur Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696522/
https://ncbi.nlm.nih.gov/pubmed/29158528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16011-2
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