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Regulatory polymorphisms in the interleukin-18 promoter are associated with hepatitis C virus clearance
The immune response is critical in determining the outcome of hepatitis C virus (HCV) infection. Interleukin (IL)-18 is a pivotal mediator of Th1/Th2 driven immune response. Two IL-18 promoter polymorphisms (-607 C/A and -137 G/C) and their haplotypes were known to affect the IL-18 expression. We ex...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674361/ https://ncbi.nlm.nih.gov/pubmed/18781864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/592047 |
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