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Fungal sphingolipids: role in the regulation of virulence and potential as targets for future antifungal therapies

INTRODUCTION: The antifungal therapy currently available includes three major classes of drugs: polyenes, azoles and echinocandins. However, the clinical use of these compounds faces several challenges: while polyenes are toxic to the host, antifungal resistance to azoles and echinocandins has been...

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Bibliographic Details
Published in:Expert Rev Anti Infect Ther
Main Authors: Fernandes, Caroline Mota, Poeta, Maurizio Del
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657966/
https://ncbi.nlm.nih.gov/pubmed/32673125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14787210.2020.1792288
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