Acylhydrazones as Antifungal Agents Targeting the Synthesis of Fungal Sphingolipids

The incidence of invasive fungal infections has risen dramatically in recent decades. Current antifungal drugs are either toxic, likely to interact with other drugs, have a narrow spectrum of activity, or induce fungal resistance. Hence, there is a great need for new antifungals, possibly with novel...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Lazzarini, Cristina, Haranahalli, Krupanandan, Rieger, Robert, Ananthula, Hari Krishna, Desai, Pankaj B., Ashbaugh, Alan, Linke, Michael J., Cushion, Melanie T., Ruzsicska, Bela, Haley, John, Ojima, Iwao, Del Poeta, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923120/
https://ncbi.nlm.nih.gov/pubmed/29507066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00156-18
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