Acylhydrazones as Antifungal Agents Targeting the Synthesis of Fungal Sphingolipids

The incidence of invasive fungal infections has risen dramatically in recent decades. Current antifungal drugs are either toxic, likely to interact with other drugs, have a narrow spectrum of activity, or induce fungal resistance. Hence, there is a great need for new antifungals, possibly with novel...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Lazzarini, Cristina, Haranahalli, Krupanandan, Rieger, Robert, Ananthula, Hari Krishna, Desai, Pankaj B., Ashbaugh, Alan, Linke, Michael J., Cushion, Melanie T., Ruzsicska, Bela, Haley, John, Ojima, Iwao, Del Poeta, Maurizio
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923120/
https://ncbi.nlm.nih.gov/pubmed/29507066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00156-18
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