Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids

Recent estimates suggest that >300 million people are afflicted by serious fungal infections worldwide. Current antifungal drugs are static and toxic and/or have a narrow spectrum of activity. Thus, there is an urgent need for the development of new antifungal drugs. The fungal sphingolipid gluco...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:mBio
المؤلفون الرئيسيون: Mor, Visesato, Rella, Antonella, Farnoud, Amir M., Singh, Ashutosh, Munshi, Mansa, Bryan, Arielle, Naseem, Shamoon, Konopka, James B., Ojima, Iwao, Bullesbach, Erika, Ashbaugh, Alan, Linke, Michael J., Cushion, Melanie, Collins, Margaret, Ananthula, Hari Krishna, Sallans, Larry, Desai, Pankaj B., Wiederhold, Nathan P., Fothergill, Annette W., Kirkpatrick, William R., Patterson, Thomas, Wong, Lai Hong, Sinha, Sunita, Giaever, Guri, Nislow, Corey, Flaherty, Patrick, Pan, Xuewen, Cesar, Gabriele Vargas, de Melo Tavares, Patricia, Frases, Susana, Miranda, Kildare, Rodrigues, Marcio L., Luberto, Chiara, Nimrichter, Leonardo, Del Poeta, Maurizio
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society of Microbiology 2015
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479701/
https://ncbi.nlm.nih.gov/pubmed/26106079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00647-15
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