Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids

Recent estimates suggest that >300 million people are afflicted by serious fungal infections worldwide. Current antifungal drugs are static and toxic and/or have a narrow spectrum of activity. Thus, there is an urgent need for the development of new antifungal drugs. The fungal sphingolipid gluco...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:mBio
Päätekijät: Mor, Visesato, Rella, Antonella, Farnoud, Amir M., Singh, Ashutosh, Munshi, Mansa, Bryan, Arielle, Naseem, Shamoon, Konopka, James B., Ojima, Iwao, Bullesbach, Erika, Ashbaugh, Alan, Linke, Michael J., Cushion, Melanie, Collins, Margaret, Ananthula, Hari Krishna, Sallans, Larry, Desai, Pankaj B., Wiederhold, Nathan P., Fothergill, Annette W., Kirkpatrick, William R., Patterson, Thomas, Wong, Lai Hong, Sinha, Sunita, Giaever, Guri, Nislow, Corey, Flaherty, Patrick, Pan, Xuewen, Cesar, Gabriele Vargas, de Melo Tavares, Patricia, Frases, Susana, Miranda, Kildare, Rodrigues, Marcio L., Luberto, Chiara, Nimrichter, Leonardo, Del Poeta, Maurizio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Microbiology 2015
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479701/
https://ncbi.nlm.nih.gov/pubmed/26106079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00647-15
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