The Future of Antifungal Drug Therapy: Novel Compounds and Targets

Fungal infections are a universal problem and are routinely associated with high morbidity and mortality rates in immunocompromised patients. Existing therapies comprise five different classes of antifungal agents, four of which target the synthesis of ergosterol and cell wall glucans. However, the...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Mota Fernandes, Caroline, Dasilva, Deveney, Haranahalli, Krupanandan, McCarthy, J. Brian, Mallamo, John, Ojima, Iwao, Del Poeta, Maurizio
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848987/
https://ncbi.nlm.nih.gov/pubmed/33229427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01719-20
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