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Blackout in the powerhouse: clinical phenotypes associated with defects in the assembly of OXPHOS complexes and the mitoribosome

Mitochondria produce the bulk of the energy used by almost all eukaryotic cells through oxidative phosphorylation (OXPHOS) which occurs on the four complexes of the respiratory chain and the F(1)–F(0) ATPase. Mitochondrial diseases are a heterogenous group of conditions affecting OXPHOS, either dire...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Hock, Daniella H., Robinson, David R. L., Stroud, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657662/
https://ncbi.nlm.nih.gov/pubmed/33151299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20190767
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