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Blackout in the powerhouse: clinical phenotypes associated with defects in the assembly of OXPHOS complexes and the mitoribosome

Mitochondria produce the bulk of the energy used by almost all eukaryotic cells through oxidative phosphorylation (OXPHOS) which occurs on the four complexes of the respiratory chain and the F(1)–F(0) ATPase. Mitochondrial diseases are a heterogenous group of conditions affecting OXPHOS, either dire...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochem J
Hauptverfasser: Hock, Daniella H., Robinson, David R. L., Stroud, David A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657662/
https://ncbi.nlm.nih.gov/pubmed/33151299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20190767
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