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Post‐GWAS Polygenic Risk Score: Utility and Challenges

Over the past decade, through genome‐wide association studies, more than 300 genetic variants have been identified to be associated with either BMD or fracture risk. These genetic variants are common in the general population, but they exert small to modest effects on BMD, suggesting that the utilit...

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Detalhes bibliográficos
Publicado no:JBMR Plus
Main Authors: Nguyen, Tuan V, Eisman, John A
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657393/
https://ncbi.nlm.nih.gov/pubmed/33210063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10411
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