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Post‐GWAS Polygenic Risk Score: Utility and Challenges

Over the past decade, through genome‐wide association studies, more than 300 genetic variants have been identified to be associated with either BMD or fracture risk. These genetic variants are common in the general population, but they exert small to modest effects on BMD, suggesting that the utilit...

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Библиографические подробности
Опубликовано в: :JBMR Plus
Главные авторы: Nguyen, Tuan V, Eisman, John A
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley & Sons, Inc. 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657393/
https://ncbi.nlm.nih.gov/pubmed/33210063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10411
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