SOX2 promotes tumor growth of esophageal squamous cell carcinoma through the AKT/mammalian target of rapamycin complex 1 signaling pathway

The transcription factor SOX2 is essential for the maintenance of embryonic stem cells and normal development of the esophagus. Our previous study revealed that the SOX2 gene is an amplification target of 3q26.3 in esophageal squamous cell carcinoma (ESCC), and that SOX2 promotes ESCC cell prolifera...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Gen, Yasuyuki, Yasui, Kohichiroh, Nishikawa, Taichiro, Yoshikawa, Toshikazu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657236/
https://ncbi.nlm.nih.gov/pubmed/23510069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12155
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