The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C

The target of rapamycin (TOR), as part of the rapamycin-sensitive TOR complex 1 (TORC1), regulates various aspects of protein synthesis. Whether TOR functions in this process as part of TORC2 remains to be elucidated. Here, we demonstrate that mTOR, SIN1 and rictor, components of mammalian (m)TORC2,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Facchinetti, Valeria, Ouyang, Weiming, Wei, Hua, Soto, Nelyn, Lazorchak, Adam, Gould, Christine, Lowry, Carolyn, Newton, Alexandra C, Mao, Yuxin, Miao, Robert Q, Sessa, William C, Qin, Jun, Zhang, Pumin, Su, Bing, Jacinto, Estela
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2486276/
https://ncbi.nlm.nih.gov/pubmed/18566586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.120
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados