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Glutathione S‐transferase P1‐1 as a target for mesothelioma treatment

Malignant pleural mesothelioma is a poorly responsive tumor known to overexpress the phase II detoxification enzyme glutathione‐S‐transferase, which catalyzes the conjugation between glutathione and platinum(II)‐containing drugs. Therefore, we evaluated the effect of the strong glutathione S‐transfe...

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Publicado en:Cancer Sci
Autores principales: De Luca, Anastasia, Pellizzari Tregno, Francesca, Sau, Andrea, Pastore, Anna, Palumbo, Camilla, Alama, Angela, Cicconi, Rosella, Federici, Giorgio, Caccuri, Anna M.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657204/
https://ncbi.nlm.nih.gov/pubmed/23121163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12061
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