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Evolution of Negative Cooperativity in Glutathione Transferase Enabled Preservation of Enzyme Function

Negative cooperativity in enzyme reactions, in which the first event makes subsequent events less favorable, is sometimes well understood at the molecular level, but its physiological role has often been obscure. Negative cooperativity occurs in human glutathione transferase (GST) GSTP1-1 when it bi...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Bocedi, Alessio, Fabrini, Raffaele, Lo Bello, Mario, Caccuri, Anna Maria, Federici, Giorgio, Mannervik, Bengt, Cornish-Bowden, Athel, Ricci, Giorgio
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207182/
https://ncbi.nlm.nih.gov/pubmed/27815499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.749507
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