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Evolution of Negative Cooperativity in Glutathione Transferase Enabled Preservation of Enzyme Function
Negative cooperativity in enzyme reactions, in which the first event makes subsequent events less favorable, is sometimes well understood at the molecular level, but its physiological role has often been obscure. Negative cooperativity occurs in human glutathione transferase (GST) GSTP1-1 when it bi...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5207182/ https://ncbi.nlm.nih.gov/pubmed/27815499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.749507 |
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