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In silico and in vitro studies reveal complement system drives coagulation cascade in SARS-CoV-2 pathogenesis

The emergence and continued spread of SARS-CoV-2 have resulted in a public health emergency across the globe. The lack of knowledge on the precise mechanism of viral pathogenesis is impeding medical intervention. In this study, we have taken both in silico and in vitro experimental approaches to unr...

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Détails bibliographiques
Publié dans:Comput Struct Biotechnol J
Auteurs principaux: Tiwari, Ritudhwaj, Mishra, Anurag R., Mikaeloff, Flora, Gupta, Soham, Mirazimi, Ali, Byrareddy, Siddappa N., Neogi, Ujjwal, Nayak, Debasis
Format: Artigo
Langue:Inglês
Publié: Research Network of Computational and Structural Biotechnology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657020/
https://ncbi.nlm.nih.gov/pubmed/33200027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.11.005
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