In silico and in vitro studies reveal complement system drives coagulation cascade in SARS-CoV-2 pathogenesis

The emergence and continued spread of SARS-CoV-2 have resulted in a public health emergency across the globe. The lack of knowledge on the precise mechanism of viral pathogenesis is impeding medical intervention. In this study, we have taken both in silico and in vitro experimental approaches to unr...

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Publicado en:Comput Struct Biotechnol J
Autores principales: Tiwari, Ritudhwaj, Mishra, Anurag R., Mikaeloff, Flora, Gupta, Soham, Mirazimi, Ali, Byrareddy, Siddappa N., Neogi, Ujjwal, Nayak, Debasis
Formato: Artigo
Lenguaje:Inglês
Publicado: Research Network of Computational and Structural Biotechnology 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657020/
https://ncbi.nlm.nih.gov/pubmed/33200027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.11.005
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