In silico and in vitro studies reveal complement system drives coagulation cascade in SARS-CoV-2 pathogenesis

The emergence and continued spread of SARS-CoV-2 have resulted in a public health emergency across the globe. The lack of knowledge on the precise mechanism of viral pathogenesis is impeding medical intervention. In this study, we have taken both in silico and in vitro experimental approaches to unr...

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Udgivet i:Comput Struct Biotechnol J
Main Authors: Tiwari, Ritudhwaj, Mishra, Anurag R., Mikaeloff, Flora, Gupta, Soham, Mirazimi, Ali, Byrareddy, Siddappa N., Neogi, Ujjwal, Nayak, Debasis
Format: Artigo
Sprog:Inglês
Udgivet: Research Network of Computational and Structural Biotechnology 2020
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Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657020/
https://ncbi.nlm.nih.gov/pubmed/33200027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.11.005
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