A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease

BACKGROUND: Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia worldwide. To date, animal models of Alzheimer’s have focused on rare familial mutations, due to a lack of frank neuropathology from models based on common disease genes. Recent multi-cohort studies of postmortem h...

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Dettagli Bibliografici
Pubblicato in:Mol Neurodegener
Autori principali: Preuss, Christoph, Pandey, Ravi, Piazza, Erin, Fine, Alexander, Uyar, Asli, Perumal, Thanneer, Garceau, Dylan, Kotredes, Kevin P., Williams, Harriet, Mangravite, Lara M., Lamb, Bruce T., Oblak, Adrian L., Howell, Gareth R., Sasner, Michael, Logsdon, Benjamin A., Carter, Gregory W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Methodology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656729/
https://ncbi.nlm.nih.gov/pubmed/33172468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00412-5
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