TMEM59 Haploinsufficiency Ameliorates the Pathology and Cognitive Impairment in the 5xFAD Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disease associated with cognitive deficits and synaptic impairments. Amyloid-β (Aβ) plaque deposition, dystrophic neurite accumulation and neurofibrillary tangles are pathological hallmarks of AD. TMEM59 has been implicated to play a role i...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Front Cell Dev Biol
Main Authors: Meng, Jian, Han, Linkun, Zheng, Naizhen, Xu, Hui, Liu, Zhaoji, Zhang, Xian, Luo, Hong, Can, Dan, Sun, Hao, Xu, Huaxi, Zhang, Yun-wu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655972/
https://ncbi.nlm.nih.gov/pubmed/33195275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.596030
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker