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Structures of a complete human V-ATPase reveal mechanisms of its assembly

Vesicular- or vacuolar-type adenosine triphosphatases (V-ATPases) are ATP-driven proton pumps comprised of a cytoplasmic V(1) complex for ATP hydrolysis and a membrane embedded V(o) complex for proton transfer. They play important roles in the acidification of intracellular vesicles, organelles, and...

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Bibliographic Details
Published in:Mol Cell
Main Authors: Wang, Longfei, Wu, Di, Robinson, Carol V., Wu, Hao, Fu, Tian-Min
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655608/
https://ncbi.nlm.nih.gov/pubmed/33065002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.09.029
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