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TREM2 ameliorates neuroinflammatory response and cognitive impairment via PI3K/AKT/FoxO3a signaling pathway in Alzheimer’s disease mice

Triggering receptor expressed on myeloid cells 2 (TREM2) has been shown with a neuroprotective function against inflammation and neuronal injury in Alzheimer’s disease (AD). However, the TREM2 induced anti-inflammatory mechanism is still not well known. In this study it has been demonstrated that th...

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Podrobná bibliografie
Vydáno v:Aging (Albany NY)
Hlavní autoři: Wang, Yaping, Lin, Yan, Wang, Linhan, Zhan, Hongrui, Luo, Xiaoting, Zeng, Yanyan, Wu, Wen, Zhang, Xingmei, Wang, Fang
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655179/
https://ncbi.nlm.nih.gov/pubmed/33065553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.104104
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