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Dexmedetomidine ameliorates lipopolysaccharide-induced acute lung injury by inhibiting the PI3K/Akt/FoxO1 signaling pathway

PURPOSE: Dexmedetomidine (DEX) has been associated with inflammation, oxidative stress, and apoptosis, but its effects on lipopolysaccharide (LPS)-induced lung injury remain uncertain. The present study explored the effects of DEX on LPS-induced lung injury and studied the possible molecular mechani...

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Detalhes bibliográficos
Publicado no:J Anesth
Main Authors: Cui, Haibin, Zhang, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8021217/
https://ncbi.nlm.nih.gov/pubmed/33821300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00540-021-02909-9
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