Formononetin ameliorates muscle atrophy by regulating myostatin‐mediated PI3K/Akt/FoxO3a pathway and satellite cell function in chronic kidney disease

Muscle atrophy is a common complication in chronic kidney disease (CKD). Inflammation and myostatin play important roles in CKD muscle atrophy. Formononetin (FMN), which is a major bioactive isoflavone compound in Astragalus membranaceus, exerts anti‐inflammatory effects and the promotion of myogeni...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Liu, Lingyu, Hu, Rong, You, Haiyan, Li, Jingjing, Liu, Yangyang, Li, Qiang, Wu, Xiaohui, Huang, Jiawen, Cai, Xiangsheng, Wang, Mingqing, Wei, Lianbo
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875933/
https://ncbi.nlm.nih.gov/pubmed/33405354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16238
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