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Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure
Neural tube closure defects are a major cause of infant mortality, with exencephaly accounting for nearly one-third of cases. However, the mechanisms of cranial neural tube closure are not well understood. Here, we show that this process involves a tissue-wide pattern of apical constriction controll...
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| 出版年: | eLife |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7655103/ https://ncbi.nlm.nih.gov/pubmed/33103996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60234 |
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