Intranasal fusion inhibitory lipopeptide prevents direct contact SARS-CoV-2 transmission in ferrets

Containment of the COVID-19 pandemic requires reducing viral transmission. SARS-CoV-2 infection is initiated by membrane fusion between the viral and host cell membranes, mediated by the viral spike protein. We have designed a dimeric lipopeptide fusion inhibitor that blocks this critical first step...

詳細記述

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書誌詳細
出版年:bioRxiv
主要な著者: de Vries, Rory D., Schmitz, Katharina S., Bovier, Francesca T., Noack, Danny, Haagmans, Bart L., Biswas, Sudipta, Rockx, Barry, Gellman, Samuel H., Alabi, Christopher A., de Swart, Rik L., Moscona, Anne, Porotto, Matteo
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654853/
https://ncbi.nlm.nih.gov/pubmed/33173865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.11.04.361154
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