A transcriptome-based classifier to determine molecular subtypes in medulloblastoma

Medulloblastoma is a highly heterogeneous pediatric brain tumor with five molecular subtypes, Sonic Hedgehog TP53-mutant, Sonic Hedgehog TP53-wildtype, WNT, Group 3, and Group 4, defined by the World Health Organization. The current mechanism for classification into these molecular subtypes is throu...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Rathi, Komal S., Arif, Sherjeel, Koptyra, Mateusz, Naqvi, Ammar S., Taylor, Deanne M., Storm, Phillip B., Resnick, Adam C., Rokita, Jo Lynne, Raman, Pichai
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654754/
https://ncbi.nlm.nih.gov/pubmed/33119584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008263
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