annoFuse: an R Package to annotate, prioritize, and interactively explore putative oncogenic RNA fusions

BACKGROUND: Gene fusion events are significant sources of somatic variation across adult and pediatric cancers and are some of the most clinically-effective therapeutic targets, yet low consensus of RNA-Seq fusion prediction algorithms makes therapeutic prioritization difficult. In addition, events...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Gaonkar, Krutika S., Marini, Federico, Rathi, Komal S., Jain, Payal, Zhu, Yuankun, Chimicles, Nicholas A., Brown, Miguel A., Naqvi, Ammar S., Zhang, Bo, Storm, Phillip B., Maris, John M., Raman, Pichai, Resnick, Adam C., Strauch, Konstantin, Taroni, Jaclyn N., Rokita, Jo Lynne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Software
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737294/
https://ncbi.nlm.nih.gov/pubmed/33317447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03922-7
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