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Total and Formal Syntheses of Fostriecin

Two formal syntheses and one total synthesis of fostriecin (1) have been achieved, as well as, the synthesis of its related congener dihydro-dephospho-fostriecin. All the routes use the Sharpless dihydroxylation to set the absolute stereochemistry at C-8/9 positions and a Leighton allylation to set...

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Detalles Bibliográficos
Publicado en:Org Chem Front
Main Authors: Dong, Gao, Li, Bohui, O’Doherty, George
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654735/
https://ncbi.nlm.nih.gov/pubmed/33184589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0qo01121e
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