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Base Editing in Human Cells to Produce Single Nucleotide Variant Clonal Cell Lines
Base editing technologies enable point mutation introduction at targeted genomic sites in mammalian cells, with higher efficiency and precision than traditional genome editing methods that employ DNA double-strand breaks, such as zinc finger nucleases (ZFNs), transcription activator-like effector nu...
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| Publicado no: | Curr Protoc Mol Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7654285/ https://ncbi.nlm.nih.gov/pubmed/33151638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpmb.129 |
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