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Monovar: single nucleotide variant detection in single cells
Current variant callers are not suitable for single-cell DNA sequencing (SCS) as they do not account for allelic dropout, false-positive errors, and coverage non-uniformity. We developed Monovar, a novel statistical method for detecting and genotyping single nucleotide variants in SCS data. Evaluati...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Methods |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4887298/ https://ncbi.nlm.nih.gov/pubmed/27088313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3835 |
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