Small compound bigelovin exerts inhibitory effects and triggers proteolysis of E2F1 in multiple myeloma cells

Multiple myeloma (MM) is a currently incurable blood cancer. Here we tested the effects of a small compound bigelovin on MM cells, and reported that it caused cell cycle arrest and subsequently induced apoptosis. Bigelovin triggered proteolysis of E2F1, which could be inhibited by caspase inhibitor....

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Liu, Jing‐Lei, Zeng, Guang‐Zhi, Liu, Xiao‐Li, Liu, Yong‐Qiang, Hu, Zhong‐Guo, Liu, Ying, Tan, Ning‐Hua, Zhou, Guang‐Biao
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2013
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654247/
https://ncbi.nlm.nih.gov/pubmed/24118350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12295
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker