Bigelovin triggered apoptosis in colorectal cancer in vitro and in vivo via upregulating death receptor 5 and reactive oxidative species

Colorectal cancer (CRC) is the third most prevalent cancer and the third highest cancer-related mortality in the United States. Bigelovin, a sesquiterpene lactone isolated from Inula helianthus aquatica, has been proven to induce apoptosis and exhibit anti-inflammatory and anti-angiogenic activities...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Mingyue, Song, Li-Hua, Yue, Grace Gar-Lee, Lee, Julia Kin-Ming, Zhao, Li-Mei, Li, Lin, Zhou, Xunian, Tsui, Stephen Kwok-Wing, Ng, Simon Siu-Man, Fung, Kwok-Pui, Tan, Ning-Hua, Lau, Clara Bik-San
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299840/
https://ncbi.nlm.nih.gov/pubmed/28181527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42176
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