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RA-XII inhibits tumour growth and metastasis in breast tumour-bearing mice via reducing cell adhesion and invasion and promoting matrix degradation

Cancer cells acquire invasive ability to degrade and adhere to extracellular matrix (ECM) and migrate to adjacent tissues. This ultimately results metastasis. Hence, the present study investigated the in vitro effects of cyclopeptide glycoside, RA-XII on cell adhesion, invasion, proliferation and ma...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Leung, Hoi-Wing, Zhao, Si-Meng, Yue, Grace Gar-Lee, Lee, Julia Kin-Ming, Fung, Kwok-Pui, Leung, Ping-Chung, Tan, Ning-Hua, Lau, Clara Bik-San
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655310/
https://ncbi.nlm.nih.gov/pubmed/26592552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16985
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