Novel PI3K/AKT targeting anti-angiogenic activities of 4-vinylphenol, a new therapeutic potential of a well-known styrene metabolite

The pneumo- and hepato-toxicity of 4-vinylphenol (4VP), a styrene metabolite, has been previously reported. Nevertheless, the present study reported the novel anti-angiogenic activities of 4VP which was firstly isolated from the aqueous extract of a Chinese medicinal herb Hedyotis diffusa. Our resul...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yue, Grace Gar-Lee, Lee, Julia Kin-Ming, Kwok, Hin-Fai, Cheng, Ling, Wong, Eric Chun-Wai, Jiang, Lei, Yu, Hua, Leung, Hoi-Wing, Wong, Yuk-Lau, Leung, Ping-Chung, Fung, Kwok-Pui, Lau, Clara Bik-San
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459151/
https://ncbi.nlm.nih.gov/pubmed/26053458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11149
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