RA-XII inhibits tumour growth and metastasis in breast tumour-bearing mice via reducing cell adhesion and invasion and promoting matrix degradation

Cancer cells acquire invasive ability to degrade and adhere to extracellular matrix (ECM) and migrate to adjacent tissues. This ultimately results metastasis. Hence, the present study investigated the in vitro effects of cyclopeptide glycoside, RA-XII on cell adhesion, invasion, proliferation and ma...

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Udgivet i:Sci Rep
Main Authors: Leung, Hoi-Wing, Zhao, Si-Meng, Yue, Grace Gar-Lee, Lee, Julia Kin-Ming, Fung, Kwok-Pui, Leung, Ping-Chung, Tan, Ning-Hua, Lau, Clara Bik-San
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655310/
https://ncbi.nlm.nih.gov/pubmed/26592552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16985
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