UGT1A1*6,1A7*3, and 1A9*22 genotypes predict severe neutropenia in FOLFIRI‐treated metastatic colorectal cancer in two prospective studies in Japan

Retrospective studies have suggested that UDP‐glucuronosyltransferase (UGT)1A1,UGT1A7, and UGT1A9 predict severe toxicity and efficacy of irinotecan‐containing regimens. We prospectively evaluated the impact of UGT1A genotypes and haplotypes on severe toxicity and efficacy in patients treated with f...

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Detaylı Bibliyografya
Yayımlandı:Cancer Sci
Asıl Yazarlar: Hazama, Shoichi, Mishima, Hideyuki, Tsunedomi, Ryouichi, Okuyama, Yusuke, Kato, Takeshi, Takahashi, Ken‐ichi, Nozawa, Hiroshi, Ando, Hideaki, Kobayashi, Michiya, Takemoto, Hiroyoshi, Nagata, Naoki, Kanekiyo, Shinsuke, Inoue, Yuka, Hamamoto, Yoshihiko, Fujita, Yusuke, Hinoda, Yuji, Okayama, Naoko, Oba, Koji, Sakamoto, Jun‐ichi, Oka, Masaaki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2013
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653527/
https://ncbi.nlm.nih.gov/pubmed/24033692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12283
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