UGT1A1*6,1A7*3, and 1A9*22 genotypes predict severe neutropenia in FOLFIRI‐treated metastatic colorectal cancer in two prospective studies in Japan

Retrospective studies have suggested that UDP‐glucuronosyltransferase (UGT)1A1,UGT1A7, and UGT1A9 predict severe toxicity and efficacy of irinotecan‐containing regimens. We prospectively evaluated the impact of UGT1A genotypes and haplotypes on severe toxicity and efficacy in patients treated with f...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cancer Sci
Main Authors: Hazama, Shoichi, Mishima, Hideyuki, Tsunedomi, Ryouichi, Okuyama, Yusuke, Kato, Takeshi, Takahashi, Ken‐ichi, Nozawa, Hiroshi, Ando, Hideaki, Kobayashi, Michiya, Takemoto, Hiroyoshi, Nagata, Naoki, Kanekiyo, Shinsuke, Inoue, Yuka, Hamamoto, Yoshihiko, Fujita, Yusuke, Hinoda, Yuji, Okayama, Naoko, Oba, Koji, Sakamoto, Jun‐ichi, Oka, Masaaki
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2013
נושאים:
Original Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653527/
https://ncbi.nlm.nih.gov/pubmed/24033692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12283
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