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Histone acetyltransferase Hbo1 destabilizes estrogen receptor α by ubiquitination and modulates proliferation of breast cancers

The estrogen receptor (ER) is a key molecule for growth of breast cancers. It has been a successful target for treatment of breast cancers. Elucidation of the ER expression mechanism is of importance for designing therapeutics for ER‐positive breast cancers. However, the detailed mechanism of ER sta...

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Библиографические подробности
Опубликовано в: :Cancer Sci
Главные авторы: Iizuka, Masayoshi, Susa, Takao, Takahashi, Yoshihisa, Tamamori‐Adachi, Mimi, Kajitani, Takashi, Okinaga, Hiroko, Fukusato, Toshio, Okazaki, Tomoki
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653525/
https://ncbi.nlm.nih.gov/pubmed/24125069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12303
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