Marked Cortisol Production by Intracrine ACTH in GIP-Treated Cultured Adrenal Cells in Which the GIP Receptor Was Exogenously Introduced

The ectopic expression of the glucose-dependent insulinotropic polypeptide receptor (GIPR) in the human adrenal gland causes significant hypercortisolemia after ingestion of each meal and leads to Cushing’s syndrome, implying that human GIPR activation is capable of robustly activating adrenal gluco...

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Bibliografische gegevens
Hoofdauteurs: Fujii, Hiroko, Tamamori-Adachi, Mimi, Uchida, Kousuke, Susa, Takao, Nakakura, Takashi, Hagiwara, Haruo, Iizuka, Masayoshi, Okinaga, Hiroko, Tanaka, Yuji, Okazaki, Tomoki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204891/
https://ncbi.nlm.nih.gov/pubmed/25334044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110543
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