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Intrinsic ubiquitin E3 ligase activity of histone acetyltransferase Hbo1 for estrogen receptor α

Estrogen receptors (ER) are important transcription factors to relay signals from estrogen and to regulate proliferation of some of breast cancers. The cycling of estrogen-induced DNA binding and ubiquitin-linked proteolysis of ER potentiates ER-mediated transcription. Indeed, several transcriptiona...

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Detalhes bibliográficos
Publicado no:Proc Jpn Acad Ser B Phys Biol Sci
Main Authors: IIZUKA, Masayoshi, SUSA, Takao, TAMAMORI-ADACHI, Mimi, OKINAGA, Hiroko, OKAZAKI, Tomoki
Formato: Artigo
Idioma:Inglês
Publicado em: The Japan Academy 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5713178/
https://ncbi.nlm.nih.gov/pubmed/28769019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.93.030
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