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X-ray diffraction and second harmonic imaging reveal new insights into structural alterations caused by pressure-overload in murine hearts

We demonstrate a label-free imaging approach to study cardiac remodeling of fibrotic and hypertrophic hearts, bridging scales from the whole organ down to the molecular level. To this end, we have used mice subjected to transverse aortic constriction and imaged adjacent cardiac tissue sections by mi...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Nicolas, Jan-David, Khan, Amara, Markus, Andrea, Mohamed, Belal A., Toischer, Karl, Alves, Frauke, Salditt, Tim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653033/
https://ncbi.nlm.nih.gov/pubmed/33168890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76163-6
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