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Imaging of neuronal tissues by x-ray diffraction and x-ray fluorescence microscopy: evaluation of contrast and biomarkers for neurodegenerative diseases

We have used scanning X-ray diffraction (XRD) and X-ray fluorescence (XRF) with micro-focused synchrotron radiation to study histological sections from human substantia nigra (SN). Both XRF and XRD mappings visualize tissue properties, which are inaccessible by conventional microscopy and histology....

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Bibliographische Detailangaben
Veröffentlicht in:Biomed Opt Express
Hauptverfasser: Carboni, Eleonora, Nicolas, Jan-David, Töpperwien, Mareike, Stadelmann-Nessler, Christine, Lingor, Paul, Salditt, Tim
Format: Artigo
Sprache:Inglês
Veröffentlicht: Optical Society of America 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654783/
https://ncbi.nlm.nih.gov/pubmed/29082068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.8.004331
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