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Recent developments in anticancer kinase inhibitors based on the pyrazolo[3,4-d]pyrimidine scaffold

Pyrazolo[3,4-d]pyrimidines have become of significant interest for the medicinal chemistry community as a privileged scaffold for the development of kinase inhibitors to treat a range of diseases, including cancer. This fused nitrogen-containing heterocycle is an isostere of the adenine ring of ATP,...

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Detalhes bibliográficos
Publicado no:RSC Med Chem
Main Authors: Baillache, Daniel J., Unciti-Broceta, Asier
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652001/
https://ncbi.nlm.nih.gov/pubmed/33479617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00227e
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