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Synthesis and Anticancer Activity of Some New Pyrazolo[3,4-d]pyrimidin-4-one Derivatives

3,6-Dimethyl-1-phenyl-1H-pyrazolo[3,4-d][1,3]oxazin-4-one (3) was prepared by hydrolysis of ethyl 5-amino-3-methyl-1-phenyl-1H-pyrazole-4-carboxylate (1) to afford the corresponding carboxylic acid 2, which was reacted with acetic anhydride to give 3. The pyrazolo[3,4-d][1,3]oxazin-4-one 3 was react...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Abdellatif, Khaled R. A., Abdelall, Eman K. A., Abdelgawad, Mohamed A., Ahmed, Rasha R., Bakr, Rania B.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270843/
https://ncbi.nlm.nih.gov/pubmed/24647032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19033297
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