EPCO-16. LACTIC ACID IS AN EPIGENETIC METABOLITE THAT DRIVES GLIOBLASTOMA SURVIVAL AND GROWTH

Glioblastoma (GBM) is the most common primary malignant brain tumor with an unfavorable prognosis and a reprogrammed metabolism. While tumors utilize glucose, there are other carbon sources at their disposal. Originally considered as a waste product of glucose catabolism, lactate accumulates to a si...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Torrini, Consuelo, Nguyen, Trang, Shu, Chang, Mela, Angeliki, Humala, Nelson, Mahajan, Aayushi, Karpel-Massler, Georg, Bruce, Jeffrey, Canoll, Peter, Siegelin, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
(Epi)Genetics and Computational Omics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651552/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.295
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