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PATH-17. NOVEL DUAL HISTONE 3 K27M AND G34R POINT MUTATIONS IN A MIDLINE GLIOMA

BACKGROUND: Histone H3 alterations due to mutations on H3F3A and HIST1H3B genes, have in recent years been associated with distinct entities and tumor locations within the context of infiltrative gliomas. H3K27M is associated with a midline location and is included in the WHO 2016 as the diffuse mid...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Pan, Peter, Bale, Tejus, Miller, Alexandra, Ladanyi, Marc, Rosenblum, Marc, Haggiagi, Aya
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651525/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.699
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