PATH-17. NOVEL DUAL HISTONE 3 K27M AND G34R POINT MUTATIONS IN A MIDLINE GLIOMA

BACKGROUND: Histone H3 alterations due to mutations on H3F3A and HIST1H3B genes, have in recent years been associated with distinct entities and tumor locations within the context of infiltrative gliomas. H3K27M is associated with a midline location and is included in the WHO 2016 as the diffuse mid...

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Vydáno v:Neuro Oncol
Hlavní autoři: Pan, Peter, Bale, Tejus, Miller, Alexandra, Ladanyi, Marc, Rosenblum, Marc, Haggiagi, Aya
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Molecular Pathology & Classification
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651525/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.699
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